據歐盟食品安全局(EFSA)消息,12月7日歐盟食品安全局營養素資源與食品添加劑專家組就再次β-環糊精作為食品添加劑的安全性發布意見。
β-環糊精由7個 α-1,4-鏈接 d-葡糖基構成的環狀寡糖。在1996年歐盟專家組將其ADI定為5mg/kg體重/天。歐盟專家組經過再次評估后認為,ADI設定為5mg/kg體重/天仍然合理。然而在現有報道以及使用量的情況下,在品牌忠誠的情況下,所有人群的攝入量會超過ADI數值,嬰兒平均值統計(mean percentile)以及所有人群95值統計(95th percentile)的情況除外。
部分原文報道如下:
he EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re-evaluating the safety of β-cyclodextrin (E 459) as a food additive. β-Cyclodextrin is a non-reducing cyclic oligosaccharide consisting of seven α-1,4-linked d-glucopyranosyl units. The Scientific Committee on Food (SCF) allocated an acceptable daily intake (ADI) of 5 mg/kg body weight (bw) per day to β-cyclodextrin (E 459) in 1996.
The Panel concluded that, based on the available toxicological database, there is no reason to revise the current ADI of 5 mg/kg bw per day for β-cyclodextrin. based on the available reported use and use levels, the Panel also concluded that the ADI was exceeded in the refined brand-loyal scenario (considered the most relevant scenario) in all population groups except for infants at the mean and in all population groups at the 95th percentile.
原文鏈接:http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4628/full
日期:2016-12-13
β-環糊精由7個 α-1,4-鏈接 d-葡糖基構成的環狀寡糖。在1996年歐盟專家組將其ADI定為5mg/kg體重/天。歐盟專家組經過再次評估后認為,ADI設定為5mg/kg體重/天仍然合理。然而在現有報道以及使用量的情況下,在品牌忠誠的情況下,所有人群的攝入量會超過ADI數值,嬰兒平均值統計(mean percentile)以及所有人群95值統計(95th percentile)的情況除外。
部分原文報道如下:
he EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re-evaluating the safety of β-cyclodextrin (E 459) as a food additive. β-Cyclodextrin is a non-reducing cyclic oligosaccharide consisting of seven α-1,4-linked d-glucopyranosyl units. The Scientific Committee on Food (SCF) allocated an acceptable daily intake (ADI) of 5 mg/kg body weight (bw) per day to β-cyclodextrin (E 459) in 1996.
The Panel concluded that, based on the available toxicological database, there is no reason to revise the current ADI of 5 mg/kg bw per day for β-cyclodextrin. based on the available reported use and use levels, the Panel also concluded that the ADI was exceeded in the refined brand-loyal scenario (considered the most relevant scenario) in all population groups except for infants at the mean and in all population groups at the 95th percentile.
原文鏈接:http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4628/full
日期:2016-12-13