2025年4月24日，歐盟食品安全局就一種食品酶內切-1,3（4）-β-葡聚糖酶（endo-1,3(4)-β-glucanase）的安全性評價發布意見。
據了解，這種食品酶是由非轉基因Cellulosimicrobium funkei菌株AE-TN生產的。
經過評估，專家小組認為，該食品酶在預期的使用條件下不會引起安全問題。部分原文報道如下：
The food enzyme endo-1,3(4)-β-glucanase (3-(1–3;1–4)-β-D-glucan 3(4)-glucano?hydrolase; EC 3.2.1.6) is produced with the non-genetically modified (GM) Cellulosimicrobium funkei strain AE-TN by Amano Enzyme Inc. The production organism belongs to a species implicated in opportunistic infections in humans. In a previous evaluation, the Panel did not consider the food enzyme safe due to the presence of viable cells of the production strain in the food enzyme. As a follow-up, the applicant improved the quality assurance system by introducing a pressure check of the microfiltration step of the food enzyme manufacturing process and the production strain was no longer detected in new food enzyme batches. The Panel accepted the results. based on the new data and the previous evaluation, the Panel concluded that the food enzyme endo-1,3(4)-β-glucanase produced with the non-GM C. funkei strain AE-TN does not give rise to safety concerns under the intended conditions of use.
據了解，這種食品酶是由非轉基因Cellulosimicrobium funkei菌株AE-TN生產的。
經過評估，專家小組認為，該食品酶在預期的使用條件下不會引起安全問題。部分原文報道如下：
The food enzyme endo-1,3(4)-β-glucanase (3-(1–3;1–4)-β-D-glucan 3(4)-glucano?hydrolase; EC 3.2.1.6) is produced with the non-genetically modified (GM) Cellulosimicrobium funkei strain AE-TN by Amano Enzyme Inc. The production organism belongs to a species implicated in opportunistic infections in humans. In a previous evaluation, the Panel did not consider the food enzyme safe due to the presence of viable cells of the production strain in the food enzyme. As a follow-up, the applicant improved the quality assurance system by introducing a pressure check of the microfiltration step of the food enzyme manufacturing process and the production strain was no longer detected in new food enzyme batches. The Panel accepted the results. based on the new data and the previous evaluation, the Panel concluded that the food enzyme endo-1,3(4)-β-glucanase produced with the non-GM C. funkei strain AE-TN does not give rise to safety concerns under the intended conditions of use.
